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DNA in Virtuo visualization and exploration of 3D genomic structures

Published: 03 November 2004 Publication History

Abstract

In this paper, we address the potential offered by Virtual Reality and scientific simulation for 3D modeling and immersive visualization of huge genomic sequences. Advanced work on 3D data modeling and structuring is proposed. In Bioinformatics, DNA sequences are often represented within linear format. However, they also have a three-dimensional structure potentially suitable for genomic analysis. The representation of such 3D structure allows biologists to observe and analyze genomes in an interactive way at different levels: from gene to chromosome. We developed a powerful software platform that provides a new point of view for sequences analysis: <i>ADN-Viewer</i>. Nevertheless, a classical eukaryotic chromosome of 40 million base pairs requires about 6 Gbytes of 3D data. In order to manage these huge masses of data in real-time, we designed various scene management algorithms and immersive human-computer interaction for <i>user-friendly</i> data exploration.

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  • (2022)Review of Innovative Immersive Technologies for Healthcare ApplicationsInnovations in Digital Health, Diagnostics, and Biomarkers10.36401/IDDB-21-042:2022(27-39)Online publication date: 29-Mar-2022
  • (2022)Vivern–A Virtual Environment for Multiscale Visualization and Modeling of DNA NanostructuresIEEE Transactions on Visualization and Computer Graphics10.1109/TVCG.2021.310632828:12(4825-4838)Online publication date: 1-Dec-2022
  • (2016)Computational 3D Assembling Methods for DNAIEEE/ACM Transactions on Computational Biology and Bioinformatics10.1109/TCBB.2015.251000813:6(1068-1085)Online publication date: 1-Nov-2016
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cover image ACM Conferences
AFRIGRAPH '04: Proceedings of the 3rd international conference on Computer graphics, virtual reality, visualisation and interaction in Africa
November 2004
176 pages
ISBN:1581138636
DOI:10.1145/1029949
Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is permitted. To copy otherwise, or republish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from [email protected]

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Published: 03 November 2004

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Author Tags

  1. 3D modeling
  2. bioinformatics
  3. human-computer interaction
  4. scientific visualization
  5. virtual reality

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Cited By

View all
  • (2022)Review of Innovative Immersive Technologies for Healthcare ApplicationsInnovations in Digital Health, Diagnostics, and Biomarkers10.36401/IDDB-21-042:2022(27-39)Online publication date: 29-Mar-2022
  • (2022)Vivern–A Virtual Environment for Multiscale Visualization and Modeling of DNA NanostructuresIEEE Transactions on Visualization and Computer Graphics10.1109/TVCG.2021.310632828:12(4825-4838)Online publication date: 1-Dec-2022
  • (2016)Computational 3D Assembling Methods for DNAIEEE/ACM Transactions on Computational Biology and Bioinformatics10.1109/TCBB.2015.251000813:6(1068-1085)Online publication date: 1-Nov-2016
  • (2007)A 3D pattern matching algorithm for DNA sequencesBioinformatics10.1093/bioinformatics/btl66923:6(680-686)Online publication date: 18-Jan-2007
  • (2006)Immersive Visualization for Genome Exploration and Analysis2006 2nd International Conference on Information & Communication Technologies10.1109/ICTTA.2006.1684982(3510-3515)Online publication date: 2006
  • (2006)Visual Mining for Microarray Knowledge Discovery2006 2nd International Conference on Information & Communication Technologies10.1109/ICTTA.2006.1684981(3504-3509)Online publication date: 2006
  • (2005)Immersive graph-based visualization and exploration of biological data relationshipsData Science Journal10.2481/dsj.4.1894(189-194)Online publication date: 2005
  • (2005)Visual data mining of genomic databases by immersive graph-based explorationProceedings of the 3rd international conference on Computer graphics and interactive techniques in Australasia and South East Asia10.1145/1101389.1101418(143-146)Online publication date: 29-Nov-2005
  • (2005)Managing deformable objects in cluster renderingProceedings of the 5th international conference on Computational Science - Volume Part II10.1007/11428848_36(290-297)Online publication date: 22-May-2005

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