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ABSTRACT
Great strides were made during the 20th Century to improve the diagnosis and treatment of many common diseases, but those strides are not enough. Millions die each year from diseases that are chronic and complex. To meet the challenge of combating these complex diseases, biomedical research in the 21st Century must take advantage of advanced discovery in information technology to create interventions that are predictive, personalized, and preemptive. [1] At the patient level, 21st Century medicine must use the precision of evidence-based diagnostic systems to deliver highly tailored treatment regimens in precise, effective ways. At the population level, 21st Century disease control must use the power of connective surveillance infrastructures to identify targets of opportunity early, and to apply current knowledge for intervention in rapidly diffusing ways. To achieve these goals, population health in the 21st century must rely on the connective power of powerful health informatics infrastructures, or cyberinfrastructures in health. REFERENCES
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