ABSTRACT
The principal reasons for the construction of computer models of systemic physiological models are no different from the problem of theoretical computations in any other field. Systemic physiology, by which I mean the written literature of the subject as distinct from the process of acquiring such information, is voluminous, undoubtedly redundant, and probably contains many contradictions. Moreover, it is difficult to separate opinion from observation, correlation from imputations of causality. Nevertheless, this is the milieu on which the intelligent physiologist functions. He pushes the frontier forward in every decreasing salients because the weight of past experience becomes more and more unmanageable.
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