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Automatic hippocampus localization in histological images using PSO-based deformable models

Published: 12 July 2011 Publication History

Abstract

The Allen Brain Atlas (ABA) is a cellular-resolution, genome-wide map of gene expression in the mouse brain which allows users to compare gene expression patterns in neuroanatomical structures. The correct localization of the structures is the first step to carry on this comparison in an automatic way.
In this paper we present a completely automatic tool for the localization of the hippocampus that can be easily adapted also to other subcortical structures. This goal is achieved in two distinct phases.
The first phase, called "best reference slice selection", is performed by comparing the image of the brain with a reference Atlas provided by ABA using a two-step affine registration. By doing so the system is able to automatically find to which brain section the image corresponds and wherein the image the hippocampus is roughly located.
The second phase, the proper "hippocampus localization", is based on a method that combines Particle Swarm Optimization (PSO) and a novel technique inspired by Active Shape Models (ASMs). The hippocampus is found by adapting a deformable model derived statistically, in order to make it overlap with the hippocampus image.
Experiments on a test set of 120 images yielded a perfect or good localization in 89.2% of cases.

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  • (2022)Robust Hippocampus Localization From Structured Magnetic Resonance Imaging Using Similarity Metric LearningIEEE Access10.1109/ACCESS.2021.313782410(7141-7152)Online publication date: 2022
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    cover image ACM Conferences
    GECCO '11: Proceedings of the 13th annual conference companion on Genetic and evolutionary computation
    July 2011
    1548 pages
    ISBN:9781450306904
    DOI:10.1145/2001858
    Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than ACM must be honored. Abstracting with credit is permitted. To copy otherwise, or republish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from [email protected]

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    Publication History

    Published: 12 July 2011

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    Author Tags

    1. active shape models
    2. affine registration
    3. allen brain atlas
    4. automatic localization
    5. hippocampus
    6. particle swarm optimization

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    View all
    • (2022)Robust Hippocampus Localization From Structured Magnetic Resonance Imaging Using Similarity Metric LearningIEEE Access10.1109/ACCESS.2021.313782410(7141-7152)Online publication date: 2022
    • (2019)A Decennary Survey on Artificial Intelligence Methods for Image SegmentationAdvanced Engineering Optimization Through Intelligent Techniques10.1007/978-981-13-8196-6_27(291-311)Online publication date: 10-Jul-2019
    • (2016)A survey on image segmentation using metaheuristic-based deformable modelsApplied Soft Computing10.1016/j.asoc.2016.03.00444:C(1-29)Online publication date: 1-Jul-2016
    • (2014)Evolutionary image analysis and signal processingProceedings of the Companion Publication of the 2014 Annual Conference on Genetic and Evolutionary Computation10.1145/2598394.2605359(795-818)Online publication date: 12-Jul-2014
    • (2013)Segmentation of histological images using a metaheuristic-based level set approachProceedings of the 15th annual conference companion on Genetic and evolutionary computation10.1145/2464576.2466808(1455-1462)Online publication date: 6-Jul-2013
    • (2013)Automatic hippocampus localization in histological images using Differential Evolution-based deformable modelsPattern Recognition Letters10.1016/j.patrec.2012.10.01234:3(299-307)Online publication date: 1-Feb-2013
    • (2012)First results and future developments of the MIBISOC Project in the IBISlab of the university of parmaProceedings of the 14th annual conference companion on Genetic and evolutionary computation10.1145/2330784.2330865(509-516)Online publication date: 7-Jul-2012
    • (2012)libCudaOptimizeProceedings of the 14th annual conference companion on Genetic and evolutionary computation10.1145/2330784.2330803(117-124)Online publication date: 7-Jul-2012
    • (2012)Automatic segmentation of hippocampus in histological images of mouse brains using deformable models and random forest2012 25th IEEE International Symposium on Computer-Based Medical Systems (CBMS)10.1109/CBMS.2012.6266318(1-4)Online publication date: Jun-2012

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